Stimulation of Nerve Growth Factor Production by Pyrroloquinoline Quinone and Its Derivativesin Vitroandin Vivo
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چکیده
منابع مشابه
Production and Radioprotective Effects of Pyrroloquinoline Quinone
Pyrroloquinoline quinone (PQQ) was produced by fermentation of the Methylovorus sp. MP688 strain and purified by ion-exchange chromatography, crystallization and recrystallization. The yield of PQQ reached approximately 125 mg/L and highly pure PQQ was obtained. To determine the optimum dose of PQQ for radioprotection, three doses (2 mg/kg, 4 mg/kg, 8 mg/kg) of PQQ were orally administrated to ...
متن کاملProduction of pyrroloquinoline quinone by using methanol-utilizing bacteria.
A large number of methanol-utilizing bacteria were screened for extracellular production of pyrroloquinoline quinone (PQQ) by using methanol as the carbon and energy sources. Of the bacteria selected, Hyphomicrobium sp. strain TK 0441 was examined for PQQ production by using a jar fermentor. The amount of PQQ in the broth and the level of methanol dehydrogenase activity in the cells were increa...
متن کاملFactors relevant in bacterial pyrroloquinoline quinone production.
Quinoprotein content and levels of external pyrroloquinoline quinone (PQQ) were determined for several bacteria under a variety of growth conditions. From these data and those from the literature, a number of factors can be indicated which are relevant for PQQ production. Synthesis of PQQ is only started if synthesis of a quinoprotein occurs, but quinoprotein synthesis does not depend on PQQ sy...
متن کاملFactors affecting the production of pyrroloquinoline quinone by the methylotrophic bacterium W3A1.
Two variants of the methylotrophic bacterium W3A1, designated W3A1-S (slimy) and W3A1-NS (nonslimy), were compared with respect to their ability to grow in batch culture on the C1 substrates methylamine, methanol, and trimethylamine. Substrate utilization, cell density, pH, cellular and soluble polysaccharide production, and concentrations of the enzymes methylamine dehydrogenase, trimethylamin...
متن کاملOn the Inside Pyrroloquinoline Quinone: A New Plant Growth Promotion Factor
Plant growth-promoting rhizobacteria (PGPR) are bacteria that colonize plant roots and enhance plant growth by a wide variety of mechanisms. The use of PGPR in sustainable agriculture is steadily increasing and offers an attractive way to replace chemical fertilizers, pesticides, and supplements. PGPR have been applied to various crops to enhance growth, seed emergence, crop yield, and disease ...
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ژورنال
عنوان ژورنال: Bioscience, Biotechnology, and Biochemistry
سال: 1993
ISSN: 0916-8451,1347-6947
DOI: 10.1271/bbb.57.1231